02D24E7D-67D3-4337-92AC-2BC3D8171DB7 Yes A72A1DAE-6539-461D-A000-4179652AA390
June Sale: $1,350 in savings
0 1
Copy Discount Code

Code copied successfully.

Home Lux Comfort
How to Clean Mouse Droppings from Mattress: A Comprehensive Guide

How to Clean Mouse Droppings from Mattress: A Comprehensive Guide

How to Clean Mouse Droppings from Mattress: A Comprehensive Guide

Encountering mouse droppings on your mattress is not only unpleasant but also a health hazard. Proper cleaning techniques are crucial to eliminate any traces of contamination and ensure your mattress remains safe for use.

Mouse Droppings Mattress Cleanup

Effective removal of mouse droppings involves several steps:

  1. Safety First: Wear gloves and a mask to avoid direct contact and inhalation of harmful particles. Ventilate the room by opening windows.

  2. Initial Cleanup: Carefully pick up the droppings with paper towels. Avoid vacuuming initially, as this can spread harmful particles into the air.

  3. Disinfecting the Area: Use a disinfectant spray specifically designed to kill bacteria and viruses. Let it sit for the recommended time before wiping.

Can Mouse Urine Be Cleaned from Mattress?

Cleaning mouse urine from a mattress is possible, but it requires immediate and thorough action due to its potential to leave stains and odors:

How to Clean Mouse Urine from a Mattress

A detailed guide to effectively removing mouse urine from a mattress:

  1. Blotting the Urine: Use absorbent paper towels or a clean, dry cloth to blot up as much urine as possible. Press firmly to absorb urine deep in the mattress fibers.

  2. Enzymatic Cleaner Application: Enzymatic cleaners are specifically designed to break down urine and neutralize odors. Spray the cleaner generously on the affected area and let it sit for the recommended time.

  3. Gentle Scrubbing: If the stain persists, gently scrub the area with a soft-bristle brush. This helps the cleaner penetrate deeper into the fabric.

  4. Rinsing the Area: After the cleaner has done its work, dab the area with a damp cloth to remove any residue of the cleaning solution.

  5. Air Drying: Allow the mattress to air dry completely. Position fans to circulate air around the mattress or place it in a well-ventilated area.

  6. Repeat if Needed: For persistent stains or odors, a second application of the enzymatic cleaner may be necessary.

  7. Baking Soda for Residual Odors: After the mattress is dry, sprinkle baking soda over the cleaned area to absorb any lingering odors. Leave it for several hours before vacuuming it off.

  8. Preventive Measures: Consider using a waterproof mattress protector in the future to safeguard against accidents and make cleaning easier.

For individuals concerned about the cleanliness and maintenance of their mattress, especially in situations like mouse infestation, a Puffy Lux Mattress might be an ideal choice. Designed with advanced materials, it is easier to clean and maintain, offering a hygienic sleep environment.

Interested in how Puffy stacks up against other brands? Check out our mattress comparisons: Puffy vs Purple, Puffy vs Nectar, Puffy vs Casper, Puffy vs Leesa, Puffy vs Saatva, Puffy vs DreamCloud, and Puffy vs Tuft and Needle.

How to Remove Mouse Odor from Mattress

Eliminating mouse odor from a mattress is essential for maintaining a fresh and hygienic sleeping environment. Here’s how you can tackle this issue:

  1. Deep Cleaning with Vinegar: Vinegar is a natural odor neutralizer. Mix a solution of equal parts white vinegar and water. Lightly spray it on the mattress, focusing on the affected areas. Avoid soaking the mattress.

  2. Baking Soda Treatment: After the vinegar solution has dried, sprinkle a generous amount of baking soda over the entire mattress. Baking soda helps absorb residual odors and moisture. Leave the baking soda on for several hours or overnight for maximum effectiveness.

  3. Thorough Vacuuming: Vacuum the mattress thoroughly to remove the baking soda along with any trapped odors.

  4. Sunlight Exposure: If possible, place the mattress in direct sunlight for a few hours. Sunlight is a natural disinfectant and can help eliminate lingering odors.

  5. Repeat if Necessary: For persistent odors, repeat the vinegar and baking soda treatment. Sometimes, multiple treatments are needed to completely remove the odor.

Check out Puffy mattress reviews from real customers and see how we compare with other brands.

How to Clean Mouse Poop off a Mattress

Cleaning mouse droppings from a mattress should be done carefully to prevent the spread of harmful pathogens:

  1. Initial Safety Precautions: Wear gloves and a mask to avoid direct contact and inhalation of particles from the droppings.

  2. Careful Removal: Gently pick up the droppings with a paper towel. It’s important to avoid vacuuming initially as it can aerosolize harmful particles.

  3. Disinfecting the Area: Use a disinfectant spray that’s effective against bacteria and viruses. Spray the affected area and let it sit for the time recommended by the product.

  4. Wiping and Rinsing: After the disinfectant has sat, wipe the area with a damp cloth to remove any residues.

  5. Drying the Mattress: Let the mattress air dry completely. Ensure good ventilation in the room or use a fan to expedite the drying process.

  6. Final Vacuuming: Once the mattress is dry, vacuum the area thoroughly to ensure all residue from the droppings is removed.

In scenarios where mattress hygiene is a concern, such as cleaning after mouse droppings, opting for Puffy mattresses could be beneficial. Their construction and fabric are designed for ease of cleaning, helping to restore your mattress to a pristine condition more efficiently.

Use our store locator to find the closest furniture or mattress store near you and feel the cloudlike comfort of our Puffy Mattress in person.


Dealing with mouse droppings and urine on a mattress requires meticulous cleaning and disinfection. Following these guidelines will help ensure your mattress is not only clean but also safe and hygienic for continued use. Regular cleaning and using protective covers can further safeguard your mattress against future infestations and contamination.

Get Your Puffy Lux Mattress

article ad savings icon $1,350 in savings

Transform your comfort with the Puffy Lux.

Relax into award-winning comfort with this hybrid mattress:

  • 8 layers of cloudlike luxury.
  • Medium-plush feel.
  • Gel-infused cooling.
  • 101-night sleep trial.

Shop the award-winning Puffy collection.

puffy mattresss

Choose your award-winning mattress.

Experience the cloudlike comfort and support of our hybrid and memory foam mattresses.

  • 4 luxury mattresses
  • All sleeper types
  • Made in the USA

Prices start from $599

puffy bed frame

Customize your comfort with a bed frame.

Upgrade your sleep with our stylish and supportive bed frames, bases, and foundations.

  • Support for all mattresses
  • Adjustable comfort options
  • Quick and easy setup

Prices start from $152

puffy beddings

Elevate your sleep with luxury bedding.

Add luxury to bedtime with our silky soft sheets, protectors, blankets, and more.

  • Premium materials
  • Contemporary style
  • Ultra-soft comfort

Prices start from $59


Puffy is ranked America’s #1
luxury mattress.

Hear from
satisfied Puffy sleepers about why they give our award-winning comfort 5 stars.


Find official Puffy
mattress stores near you.

Try out the cloudlike comfort of the luxury Puffy mattress collection before you buy at our partner stores across the USA.


Save $1,425 when you buy any Puffy mattress. Verify your eligibility for our: